Theory Nexus

The history of DNA sequencing can be traced back to the early 1970s when Sanger, a British biochemist, developed a method to determine the order of nucleotides in a DNA molecule. This technique, known as Sanger sequencing, was the first method for determining the complete sequence of an organism's genome. Since then, DNA sequencing technology has undergone significant advancements, leading to the development of high-throughput sequencing techniques that allow for the rapid and cost-effective sequencing of entire genomes. These advancements have enabled researchers to uncover the molecular basis of many diseases, understand the evolutionary history of living organisms, and explore the diversity of life on Earth. This article explores the history of DNA sequencing, the technological advancements that have led to the current state of the art, and the impact that these advances have had on scientific research. The Early Days of DNA Sequencing Sanger sequencing, developed by Fredrick S...